Description
Melanotan I (Afamelanotide) Peptide Overview
Melanotan I, also known as Afamelanotide, is a synthetic analog of alpha-melanocyte–stimulating hormone (α-MSH). It is widely used in research for its ability to bind to melanocortin receptors, particularly MC1R, making it valuable in studies of melanin synthesis, photoprotection pathways, and receptor-mediated signaling.
Research Applications
Melanotan I is utilized in laboratory and analytical studies involving:
- Melanin production and pigmentation research
- Melanocortin receptor (MC1R) signaling studies
- Photobiology and UV-response research
- Peptide-receptor binding analysis
- Molecular and cellular signaling investigations
Mechanism of Action
Melanotan I binds to melanocortin receptors, especially MC1R, which are involved in regulating melanin synthesis pathways. This interaction is studied to better understand:
- Cellular pigmentation signaling
- Receptor activation and downstream pathways
- Molecular responses to environmental stimuli
Handling & Storage (Research Use)
- Store lyophilized peptide at -20°C or colder
- After reconstitution, store at 2–8°C
- Avoid repeated freeze–thaw cycles
- Protect from light and contamination
Quality & Research Use
Each batch of Melanotan I is prepared to meet strict laboratory standards, supporting consistency, purity, and reproducibility in research environments.
⚠️ For research and educational purposes only. Not for human or veterinary use.





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